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1-(2,6-dichlorophenyl) guanidine

1-(2,6-dichlorophenyl) guanidine

Catalogue No.: VL281009
CAS No.: 39075-78-0

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Name: 1-(2,6-dichlorophenyl) guanidine
Catalogue No. VL281009
CAS No. 39075-78-0
Molecular Formula C7H7ClN3
Molecular Weight 204.05
Status In-stock
IUPAC Name 2.6-Dichlorophenylguanidin
Description 1-(2,6-dichlorophenyl) guanidine (CAS No: 39075-78-0) or 2.6-Dichlorophenylguanidin is an impurity of clonidine. Clonidine is known to decrease and sometimes eliminate objective signs and symptoms of opiate withdrawal. It shows its activity by increasing neuronal activity in areas like the locus cœruleus which are managed by both alpha-2 adrenergic and opiate receptors.
References Glassman, A., et al. “Cigarette Craving, Smoking Withdrawal, and Clonidine.” Science, vol. 226, no. 4676, Nov. 1984, pp. 864–66, https://doi.org/10.1126/science.6387913. ‌Gold, MarkS., et al. “CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS.” The Lancet, vol. 312, no. 8090, Sept. 1978, pp. 599–602, https://doi.org/10.1016/s0140-6736(78)92823-4.

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