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17β-Carboxy-17-Desoxy Dexamethasone

17β-Carboxy-17-Desoxy Dexamethasone

Catalogue No.: VL273002
CAS No.: 75262-69-0

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Name: 17β-Carboxy-17-Desoxy Dexamethasone
Catalogue No. VL273002
CAS No. 75262-69-0
Molecular Formula C21H27FO4
Molecular Weight 362.44
Status In-stock
IUPAC Name (11β,16α,17β)-9-Fluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic Acid
Synonyms 20-Carboxy-17-Desoxy Related Compound
Appearance Off white powder
Description 17β-Carboxy-17-Desoxy Dexamethasone (CAS No: 75262-69-0) or 20-Carboxy-17-Desoxy Related Compound is a metabolite of Dexamethasone which controls T cell survival, growth, and differentiation and hinders the induction of nitric oxide synthase.
References ‌Matter, Brock, et al. “Dexamethasone Degradation in Aqueous Medium and Implications for Correction of in Vitro Release from Sustained Release Delivery Systems.” AAPS PharmSciTech, vol. 20, no. 8, Oct. 2019,https://doi.org/10.1208/s12249-019-1508-7.‌Riccardi, C., et al. “Glucocorticoid Hormone-Induced Modulation of Gene Expression and Regulation of T-Cell Death: Role of GITR and GILZ, Two Dexamethasone-Induced Genes.” Cell Death & Differentiation, vol. 6, no. 12, Nov. 1999, pp. 1182–89,https://d

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