| Name: | 17β-Carboxy-17-Desoxy Dexamethasone |
| Catalogue No. | VL273002 |
| CAS No. | 75262-69-0 |
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 |
| Status | In-stock |
| IUPAC Name | (11β,16α,17β)-9-Fluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic Acid |
| Synonyms | 20-Carboxy-17-Desoxy Related Compound |
| Appearance | Off white powder |
| Description | 17β-Carboxy-17-Desoxy Dexamethasone (CAS No: 75262-69-0) or 20-Carboxy-17-Desoxy Related Compound is a metabolite of Dexamethasone which controls T cell survival, growth, and differentiation and hinders the induction of nitric oxide synthase. |
| References | Matter, Brock, et al. “Dexamethasone Degradation in Aqueous Medium and Implications for Correction of in Vitro Release from Sustained Release Delivery Systems.” AAPS PharmSciTech, vol. 20, no. 8, Oct. 2019,https://doi.org/10.1208/s12249-019-1508-7.Riccardi, C., et al. “Glucocorticoid Hormone-Induced Modulation of Gene Expression and Regulation of T-Cell Death: Role of GITR and GILZ, Two Dexamethasone-Induced Genes.” Cell Death & Differentiation, vol. 6, no. 12, Nov. 1999, pp. 1182–89,https://d |
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