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3-Deoxy 3-Chloro Abiraterone

3-Deoxy 3-Chloro Abiraterone

Catalogue No.: VL830022
CAS No.: N/A

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Name: 3-Deoxy 3-Chloro Abiraterone
Catalogue No. VL830022
CAS No. N/A
Molecular Formula C24H30ClN
Molecular Weight 367.96
Status Under Development
IUPAC Name 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethan-1-one
Description 3-Deoxy 3-Chloro Abiraterone(CAS No: N/A) or 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethan-1-one, it is poorly absorbed and is susceptible to hydrolysis by esterases and is an orally active inhibitor of the steroidal enzyme CYP17A1 that is used in the treatment of prostate cancer.
References Goldberg, Tamara, and Evangelina Berrios-Colon. “Abiraterone (Zytiga), a Novel Agent for the Management of Castration-Resistant Prostate Cancer.” Pharmacy and Therapeutics, vol. 38, no. 1, 1 Jan. 2013, pp. 23–26, www.ncbi.nlm.nih.gov/pmc/articles/PMC3628169/.

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