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4 Hydroxymethyl 5 methylimidazole

4 Hydroxymethyl 5 methylimidazole

Catalogue No.: VE008009
CAS No.: 29636-87-1

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Name: 4 Hydroxymethyl 5 methylimidazole
Catalogue No. VE008009
CAS No. 29636-87-1
Molecular Formula C5H8N2O
Molecular Weight 112.13 g/mol
Status In-Stock
IUPAC Name (4-methyl-1H-imidazol-5-yl)methanol
Description 4 Hydroxymethyl 5 methylimidazole (CAS No: 29636-87-1) or (4-methyl-1H-imidazol-5-yl)methanol is a derivative of Cimetidine. Cimetidine exerts its assisting effects on acid-peptic disorders by blocking gastric acid secretion. The property of cimetidine to block histamine stimulated acid secretion is present due to its antagonistic effect at parietal cells H2 receptors. Cimetidine inhibits the effects of gastrin and acetylcholine by interrupting the pathway.
References Shinya, Susumu, et al. “Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (HMATE1).” Chemical and Pharmaceutical Bulletin, vol. 69, no. 9, Sept. 2021, pp. 905–12, https://doi.org/10.1248/cpb.c21-00429. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https://doi.org/10.1056/nejm197811022991806.

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