| Name: | 4 Hydroxymethyl 5 methylimidazole |
| Catalogue No. | VE008009 |
| CAS No. | 29636-87-1 |
| Molecular Formula | C5H8N2O |
| Molecular Weight | 112.13 g/mol |
| Status | In-Stock |
| IUPAC Name | (4-methyl-1H-imidazol-5-yl)methanol |
| Description | 4 Hydroxymethyl 5 methylimidazole (CAS No: 29636-87-1) or (4-methyl-1H-imidazol-5-yl)methanol is a derivative of Cimetidine. Cimetidine exerts its assisting effects on acid-peptic disorders by blocking gastric acid secretion. The property of cimetidine to block histamine stimulated acid secretion is present due to its antagonistic effect at parietal cells H2 receptors. Cimetidine inhibits the effects of gastrin and acetylcholine by interrupting the pathway. |
| References | Shinya, Susumu, et al. “Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (HMATE1).” Chemical and Pharmaceutical Bulletin, vol. 69, no. 9, Sept. 2021, pp. 905–12, https://doi.org/10.1248/cpb.c21-00429. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https://doi.org/10.1056/nejm197811022991806. |
