4'-Hydroxy Aceclofenac

4'-Hydroxy Aceclofenac

Catalogue No.: VL284012
CAS No.: 229308-90-1

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Name: 4'-Hydroxy Aceclofenac
Catalogue No. VL284012
CAS No. 229308-90-1
Molecular Formula C16H13Cl2NO5
Molecular Weight 370.18
Status Under Development
IUPAC Name 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester
Description 4'-Hydroxy Aceclofenac (CAS No: 229308-90-1) or 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester is a major metabolite of Aceclofenac that is a novel nonsteroidal anti-inflammatory drug (NSAID) used in patients with rheumatoid arthritis and osteoarthritis.
References ‌Yamazaki, R., et al. “A Major Metabolite of Aceclofenac, 4′-Hydroxy Aceclofenac, Suppresses the Production of Interstitial Pro-Collagenase/ProMMP-1 and Pro-Stromelysin-1/ProMMP-3 by Human Rheumatoid Synovial Cells.” Inflammation Research, vol. 49, no. 3, Mar. 2000, pp. 133–38, https://doi.org/10.1007/s000110050571. ‌

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