
Name: | 4'-Hydroxy Aceclofenac |
Catalogue No. | VL284012 |
CAS No. | 229308-90-1 |
Molecular Formula | C16H13Cl2NO5 |
Molecular Weight | 370.18 |
Status | Under Development |
IUPAC Name | 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester |
Description | 4'-Hydroxy Aceclofenac (CAS No: 229308-90-1) or 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester is a major metabolite of Aceclofenac that is a novel nonsteroidal anti-inflammatory drug (NSAID) used in patients with rheumatoid arthritis and osteoarthritis. |
References | Yamazaki, R., et al. “A Major Metabolite of Aceclofenac, 4′-Hydroxy Aceclofenac, Suppresses the Production of Interstitial Pro-Collagenase/ProMMP-1 and Pro-Stromelysin-1/ProMMP-3 by Human Rheumatoid Synovial Cells.” Inflammation Research, vol. 49, no. 3, Mar. 2000, pp. 133–38, https://doi.org/10.1007/s000110050571. |