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5 chlorohydrochlorothiazide

5 chlorohydrochlorothiazide

Catalogue No.: VL80004
CAS No.: 5233-42-1

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Name: 5 chlorohydrochlorothiazide
Catalogue No. VL80004
CAS No. 5233-42-1
Molecular Formula C7H7Cl2N3O4S2
Molecular Weight 332.18
Status In-stock
IUPAC Name 5,6-Dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide
Synonyms 5-chlorohydrochlorothiazide
Description 5-Chlorohydrochlorothiazide (CAS No.: 5233-42-1) is a potential impurity reported in the hydrochlorothiazide drug substance. Hydrochlorothiazide is a thiazide-type diuretic. It decreases blood pressure by blocking the sodium/chloride cotransporter in the early segment of the distal convoluted tubule.
References Desai, Pritesh R., et al. “Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Quantification of 15 Organic Impurities of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide in Combined Dosage Form.” Chromatographia, vol. 82, no. 5, Apr. 2019, pp. 819–33, https://doi.org/10.1007/s10337-019-03718-9.

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