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Abacavir-5'-glucuronide

Abacavir-5'-glucuronide

Catalogue No.: VL760019
CAS No.: 384329-76-4

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Name: Abacavir-5'-glucuronide
Catalogue No. VL760019
CAS No. 384329-76-4
Molecular Formula C20H26N6O7
Molecular Weight 462.47
Status Under Development
IUPAC Name (2S,3S,4S,5R)-6-((4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
Description Abacavir-5'-glucuronide (CAS No: 384329-76-4) is one of the major metabolites of an Abacavir which is a nucleoside analog, HIV-1 reverse transcriptase inhibitor, and a potent in vivo and in vitro inhibitor of HIV-1 that causes acquired immunodeficiency syndrome.
References Ravitch, Joshua R., and Caroline G. Moseley. “High-Performance Liquid Chromatographic Assay for Abacavir and Its Two Major Metabolites in Human Urine and Cerebrospinal Fluid.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 762, no. 2, Oct. 2001, pp. 165–73, https://doi.org/10.1016/s0378-4347(01)00361-9.

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