
Name: | Abacavir-5'-glucuronide |
Catalogue No. | VL760019 |
CAS No. | 384329-76-4 |
Molecular Formula | C20H26N6O7 |
Molecular Weight | 462.47 |
Status | Under Development |
IUPAC Name | (2S,3S,4S,5R)-6-((4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
Description | Abacavir-5'-glucuronide (CAS No: 384329-76-4) is one of the major metabolites of an Abacavir which is a nucleoside analog, HIV-1 reverse transcriptase inhibitor, and a potent in vivo and in vitro inhibitor of HIV-1 that causes acquired immunodeficiency syndrome. |
References | Ravitch, Joshua R., and Caroline G. Moseley. “High-Performance Liquid Chromatographic Assay for Abacavir and Its Two Major Metabolites in Human Urine and Cerebrospinal Fluid.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 762, no. 2, Oct. 2001, pp. 165–73, https://doi.org/10.1016/s0378-4347(01)00361-9. |