Abacavir EP Impurity B

Abacavir EP Impurity B

Catalogue No.: VL760001
CAS No.: 1443421-69-9

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Name: Abacavir EP Impurity B
Catalogue No. VL760001
CAS No. 1443421-69-9
Molecular Formula C18H21ClN10O
Molecular Weight 428.8
Status In-stock
IUPAC Name 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]
Synonyms Abacavir O-Pyrimidine Impurity / Abacavir Related Compound D
Appearance White solid
Description Abacavir EP Impurity B (CAS No: 1443421-69-9) or Abacavir O-Pyrimidine Impurity / Abacavir Related Compound D is synthesized by degradation of Abacavir which is nucleoside reverse transcriptase inhibitor and Its mechanism include chain termination subsequent to incorporation into the growing polynucleotide strand. It is used in the treatment of HIV infection.
References Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. ‌Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination

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