
Name: | Abacavir EP Impurity C |
Catalogue No. | VL760006 |
CAS No. | 124752-25-6 |
Molecular Formula | C11H14N6O |
Molecular Weight | 246.27 |
Status | In-stock |
IUPAC Name | (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)ethanol |
Synonyms | Abacavir USP Related Compound A / Descyclopropyl Abacavir |
Appearance | Off-White to Pale Yellow Solid |
Description | Abacavir EP Impurity C (CAS No: 124752-25-6) or Abacavir USP Related Compound A is a degradation product of Abacavir that is a nucleoside reverse transcriptase inhibitor It acts by chain termination after incorporation into the growing polynucleotide strand and is utilized in the treatment of HIV infection. |
References | Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination |