| Name: | Abacavir EP Impurity C |
| Catalogue No. | VL760006 |
| CAS No. | 124752-25-6 |
| Molecular Formula | C11H14N6O |
| Molecular Weight | 246.27 |
| Status | In-stock |
| IUPAC Name | (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)ethanol |
| Synonyms | Abacavir USP Related Compound A / Descyclopropyl Abacavir |
| Appearance | Off-White to Pale Yellow Solid |
| Description | Abacavir EP Impurity C (CAS No: 124752-25-6) or Abacavir USP Related Compound A is a degradation product of Abacavir that is a nucleoside reverse transcriptase inhibitor It acts by chain termination after incorporation into the growing polynucleotide strand and is utilized in the treatment of HIV infection. |
| References | Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination |
