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Abacavir EP Impurity C

Abacavir EP Impurity C

Catalogue No.: VL760006
CAS No.: 124752-25-6

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Name: Abacavir EP Impurity C
Catalogue No. VL760006
CAS No. 124752-25-6
Molecular Formula C11H14N6O
Molecular Weight 246.27
Status In-stock
IUPAC Name (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)ethanol
Synonyms Abacavir USP Related Compound A / Descyclopropyl Abacavir
Appearance Off-White to Pale Yellow Solid
Description Abacavir EP Impurity C (CAS No: 124752-25-6) or Abacavir USP Related Compound A is a degradation product of Abacavir that is a nucleoside reverse transcriptase inhibitor It acts by chain termination after incorporation into the growing polynucleotide strand and is utilized in the treatment of HIV infection.
References Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. ‌Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination

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