Catalogue No.: VL760005
CAS No.: 783292-37-5 (free base), 267668-71-3 (Salt)
| Name: | Abacavir EP Impurity D |
| Catalogue No. | VL760005 |
| CAS No. | 783292-37-5 (free base), 267668-71-3 (Salt) |
| Molecular Formula | C14H20Cl2N6O |
| Molecular Weight | 359.25 |
| Status | In-stock |
| IUPAC Name | [(1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol dihydrochloride |
| Synonyms | trans-Abacavir Dihydrochloride |
| Description | Abacavir EP Impurity D [CAS No: 783292-37-5 (free base), 267668-71-3 (Salt)] or Abacavir Related Compound 8 / trans-Abacavir Dihydrochloride is formed by degradation of Abacavir. Abacavir is an antiretroviral drug that acts by decreasing viral load and increased CD4+ cell count in HIV-infected patients. |
| References | Foster RH, Faulds D. Abacavir. Drugs. 1998 May;55(5):729-36; discussion 737-8. DOI: 10.2165/00003495-199855050-00018. PMID: 9585869. Kurmi, Moolchand, et al. “Stability Behaviour of Antiretroviral Drugs and Their Combinations. 5: Characterization of Novel Degradation Products of Abacavir Sulfate by Mass and Nuclear Magnetic Resonance Spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 134, Feb. 2017, pp. 372–84, https://doi.org/10.1016/j.jpba.2016.10.019. |
