| Name: | Abacavir N-Oxide Impurity |
| Catalogue No. | VL760010 |
| CAS No. | 1443421-70-2 |
| Molecular Formula | C14H18N6O2 |
| Molecular Weight | 302.34 |
| Status | In-stock |
| IUPAC Name | (1S,4R )-[4-[2-Amino-6-( cyclopropyl amino)-7-oxo-9H-purine-9-yl]cyclopent-2-en-1-yl]methanol |
| Appearance | Light Brown Solid |
| Description | Abacavir N-Oxide Impurity (CAS No: 1443421-70-2) is formed by degradation of Abacavir. Abacavir is a nucleoside analog reverse transcriptase inhibitor that inhibits isolates of HIV in vitro with a potency similar to that of zidovudine for the treatment of HIV-infected patients. |
| References | Foster RH, Faulds D. Abacavir. Drugs. 1998 May;55(5):729-36; discussion 737-8. DOI: 10.2165/00003495-199855050-00018. PMID: 9585869. Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11. |
