Overall: 0.00 $

Shopping cart is empty

Abacavir Related Compound B

Abacavir Related Compound B

Catalogue No.: VL760025
CAS No.: 141271-12-7

Sign up or login to view prices of this product

Name: Abacavir Related Compound B
Catalogue No. VL760025
CAS No. 141271-12-7
Molecular Formula C10H14ClN5O
Molecular Weight 255.7
Status Under Development
IUPAC Name (4-((2,5-diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol
Description Abacavir Related Compound B (CAS No: 141271-12-7) is an impurity of Abacavir that is a carbocyclic 2′-deoxyguanosine nucleoside analog. The mechanism includes its conversion intracellularly to a 2′-deoxyguanosine nucleoside analog that competitively restrains HIV reverse transcriptase and eliminates proviral DNA chain extension.
References Hervey, Pauline S., and Caroline M. Perry. “Abacavir.” Drugs, vol. 60, no. 2, Aug. 2000, pp. 447–79, https://doi.org/10.2165/00003495-200060020-00015. ‌Jain, Mohit, et al. “A Simple and Sensitive Method for the Ultra Trace Determination of Potential Genotoxic Impurities in Abacavir Sulfate by LC-MS.” Chemical Methodologies, vol. 2, no. 4, Sami Publishing Company, Oct. 2018, pp. 315–23, https://doi.org/10.22034/chemm.2018.66185. ‌

Similar products

Request for Quotation

Product successfully added to your cart

Question sent successfully

Benefits

Veeprho's Stock

We have synthesized more than 5000 impurities as on date

Cost Effective Scientific Solution

As we produce in grams, our prices are most competitive around the world

Certified Impurity Standards

All VEEPRHO products are supplied with certificates of analysis.

Certification

Certified by ISO, GMP, OHSAS and many more