
Name: | Abacavir Related Compound C |
Catalogue No. | VL760026 |
CAS No. | 172015-79-1 |
Molecular Formula | C11H13Cl2N5O |
Molecular Weight | 302.16 |
Status | Under Development |
IUPAC Name | (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride |
Synonyms | Abacavir 6-Chloro Analog |
Description | Abacavir Related Compound C (CAS No: 172015-79-1) or Abacavir 6-Chloro Analog is an analog of Abacavir that is the first member of the carbocyclic nucleosides family to be recommended for use for HIV. Thus having anti-HIV activity comparable to that of carbovir against HIV-1 in MT-4 cells. |
References | Canoa, Pilar, et al. “Synthesis and Anti-HIV Activity of Novel Cyclopentenyl Nucleoside Analogues of 8-Azapurine.” Chemical and Pharmaceutical Bulletin, vol. 54, no. 10, 2006, pp. 1418–20, https://doi.org/10.1248/cpb.54.1418. |