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Abacavir Related Compound C

Abacavir Related Compound C

Catalogue No.: VL760026
CAS No.: 172015-79-1

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Name: Abacavir Related Compound C
Catalogue No. VL760026
CAS No. 172015-79-1
Molecular Formula C11H13Cl2N5O
Molecular Weight 302.16
Status Under Development
IUPAC Name (1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride
Synonyms Abacavir 6-Chloro Analog
Description Abacavir Related Compound C (CAS No: 172015-79-1) or Abacavir 6-Chloro Analog is an analog of Abacavir that is the first member of the carbocyclic nucleosides family to be recommended for use for HIV. Thus having anti-HIV activity comparable to that of carbovir against HIV-1 in MT-4 cells.
References ‌Canoa, Pilar, et al. “Synthesis and Anti-HIV Activity of Novel Cyclopentenyl Nucleoside Analogues of 8-Azapurine.” Chemical and Pharmaceutical Bulletin, vol. 54, no. 10, 2006, pp. 1418–20, https://doi.org/10.1248/cpb.54.1418. ‌

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