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Abemaciclib Mesylate

Abemaciclib Mesylate

Catalogue No.: VL4990001
CAS No.: 1231930-82-7

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Name: Abemaciclib Mesylate
Catalogue No. VL4990001
CAS No. 1231930-82-7
Molecular Formula C₂₈H₃₆F₂N₈O₃S
Molecular Weight 602.7
Status Under Development
IUPAC Name N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate
Description Abemaciclib Mesylate (CAS No: 1231930-82-7) belonging to the class of Aminopyridines is an inhibitor of cyclin-dependent kinases 4 and 6 that is used in the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.
References Kim, Esther S. “Abemaciclib: First Global Approval.” Drugs, vol. 77, no. 18, Nov. 2017, pp. 2063–70, https://doi.org/10.1007/s40265-017-0840-z. ‌

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