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Abiraterone Isopropyl Ether

Abiraterone Isopropyl Ether

Catalogue No.: VL830021
CAS No.: 2484719-15-3

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Name: Abiraterone Isopropyl Ether
Catalogue No. VL830021
CAS No. 2484719-15-3
Molecular Formula C27H37NO
Molecular Weight 391.6
Status Under Development
IUPAC Name 1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethan-1-one
Description Abiraterone Isopropyl Ether (CAS No: 2484719-15-3) might be present as an impurity of Abiraterone that is a poorly water-soluble drug used in the treatment of prostate cancer that is discharged in the form of a prodrug of an acetate possessing slightly higher solubility than abiraterone in biorelevant media.
References Gala, Urvi H., et al. “The Effect of Drug Loading on the Properties of Abiraterone–Hydroxypropyl Beta Cyclodextrin Solid Dispersions Processed by Solvent Free KinetiSol® Technology.” European Journal of Pharmaceutics and Biopharmaceutics, vol. 165, Aug. 2021, pp. 52–65, https://doi.org/10.1016/j.ejpb.2021.05.001.

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