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Abiraterone N-Oxide Impurity

Abiraterone N-Oxide Impurity

Catalogue No.: VL830002
CAS No.: N/A

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Name: Abiraterone N-Oxide Impurity
Catalogue No. VL830002
CAS No. N/A
Molecular Formula C24H31NO2
Molecular Weight 365.51
Status In-stock
IUPAC Name 3-((3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxide
Description Abiraterone N-Oxide Impurity is an impurity of Abiraterone acetate, a prodrug used in the treatment of castration-resistant prostate cancer. It acts by converting itself in vivo to abiraterone which inhibits androgen biosynthesis. It induces cancerous tissue as well as the natural production of androgens.
References Mach, Samuel, et al. “Epoxidation Is the Preferred Pathway of First-Stage Metabolism of Abiraterone Acetate in Brown Bullhead (Ameiurus Nebulosus).” Environmental Science and Pollution Research, vol. 26, no. 34, Oct. 2019, pp. 34896–904, https://doi.org/10.1007/s11356-019-06568-y.

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