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Abiraterone Related Compound 5

Abiraterone Related Compound 5

Catalogue No.: VL830011
CAS No.: N/A

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Name: Abiraterone Related Compound 5
Catalogue No. VL830011
Molecular Formula C24H31F3O6S
Molecular Weight 504.56
Status Under Development
IUPAC Name Under Development
Synonyms Pregnenolone-16-ene Acetate 21-Triflate
Description Abiraterone Related Compound 5/Pregnenolone-16-ene Acetate 21-Triflate(CAS No: N/A) or (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(2-(((trifluoromethyl)sulfonyl)oxy)acetyl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate,it is poorly absorbed and is susceptible to hydrolysis by esterases and is an orally active inhibitor of the steroidal enzyme CYP17A1 that is used in the treatment of prostate cancer.
References Thakur, Abhimanyu, et al. “Abiraterone Acetate in the Treatment of Prostate Cancer.” Biomedicine & Pharmacotherapy, vol. 101, May 2018, pp. 211–218, 10.1016/j.biopha.2018.02.067.

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