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Abiraterone Sulfate Sodium Salt

Abiraterone Sulfate Sodium Salt

Catalogue No.: VL830037
CAS No.: 1993430-25-3

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Name: Abiraterone Sulfate Sodium Salt
Catalogue No. VL830037
CAS No. 1993430-25-3
Molecular Formula C24H30NO4S. Na
Molecular Weight 451.57
Status Under Development
IUPAC Name sodium (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate
Description Abiraterone Sulfate Sodium Salt (CAS No: 1993430-25-3) is an impurity of Abiraterone acetate that prevents the synthesis of testosterone by inhibition of 17a-hydroxylase. It is an antiandrogen drug approved for the treatment of metastatic castration-resistant prostate cancer.
References van Nuland, Merel, et al. “Development and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma.” Therapeutic Drug Monitoring, vol. 39, no. 3, June 2017, pp. 243–51, https://doi.org/10.1097/ftd.0000000000000387. ‌

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