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Abiratetone Succinate

Abiratetone Succinate

Catalogue No.: VL830029
CAS No.: N/A

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Name: Abiratetone Succinate
Catalogue No. VL830029
Molecular Formula C28H35NO4
Molecular Weight 449.6
Status Under Development
IUPAC Name 4-(((3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-oxobutanoic acid
Description Abiratetone Succinate(CAS No: N/A) or 4-(((3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-oxobutanoic acid, it is a decreases in PSA levels, tumor shrinkage and is inhibitor of the steroidal enzyme CYP17A1. it is used in the treatment of prostate cancer.
References Goldberg, Tamara, and Evangelina Berrios-Colon. “Abiraterone (Zytiga), a Novel Agent for the Management of Castration-Resistant Prostate Cancer.” Pharmacy and Therapeutics, vol. 38, no. 1, 1 Jan. 2013, pp. 23–26, www.ncbi.nlm.nih.gov/pmc/articles/PMC3628169/.

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