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Acarbose EP Impurity B

Acarbose EP Impurity B

Catalogue No.: VL5070003
CAS No.: N/A

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Name: Acarbose EP Impurity B
Catalogue No. VL5070003
Molecular Formula C26H43NO17
Molecular Weight 641.63
Status Under Development
IUPAC Name (1S,2S,3R,6S)-6-(((2R,3S,4S,5R,6R)-6-(((2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(((1R,4S,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)cyclohex-2-en-1-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-methyltetrahydro-2H-pyran-3-yl)amino)-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol
Description Acarbose EP Impurity B is an impurity detected in Acarbose that is used in the treatment of non-insulin-dependent or insulin-dependent diabetes. It acts by delaying the production of monosaccharides by inhibiting the a-glucosidases.
References Wang, Ya-Jun, et al. “Analysis and Determination of Anti-Diabetes Drug Acarbose and Its Structural Analogs.” Current Pharmaceutical Analysis, vol. 7, no. 1, Feb. 2011, pp. 12–20, https://doi.org/10.2174/157341211794708721. Clissold, Stephen P., and Clive Edwards. “Acarbose.” Drugs, vol. 35, no. 3, Mar. 1988, pp. 214–43, https://doi.org/10.2165/00003495-198835030-00003.

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