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Acarbose EP Impurity D

Acarbose EP Impurity D

Catalogue No.: VL5070005
CAS No.: N/A

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Name: Acarbose EP Impurity D
Catalogue No. VL5070005
CAS No. N/A
Molecular Formula C19H33NO13
Molecular Weight 483.47
Status Under Development
IUPAC Name (3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4-triol
Description Acarbose EP Impurity D is an impurity of Acarbose that delays the production of monosaccharides by inhibiting the a-glucosidases. It is used in the treatment of patients with non-insulin-dependent or insulin-dependent diabetes mellitus. It is also being studied in areas such as dumping syndrome, reactive hypoglycemia, and types IIb and IV hyperlipoproteinaemias.
References Wang, Ya-Jun, et al. “Analysis and Determination of Anti-Diabetes Drug Acarbose and Its Structural Analogs.” Current Pharmaceutical Analysis, vol. 7, no. 1, Feb. 2011, pp. 12–20, https://doi.org/10.2174/157341211794708721. Clissold, Stephen P., and Clive Edwards. “Acarbose.” Drugs, vol. 35, no. 3, Mar. 1988, pp. 214–43, https://doi.org/10.2165/00003495-198835030-00003.

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