Acebutolol EP Impurity D

Acebutolol EP Impurity D

Catalogue No.: VL4900005
CAS No.: 57898-80-3

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Name: Acebutolol EP Impurity D
Catalogue No. VL4900005
CAS No. 57898-80-3
Molecular Formula C14H22N2O3
Molecular Weight 266.34
Status Under Development
IUPAC Name 1-[5-Amino-2-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]ethanone
Description Acebutolol EP Impurity D (CAS No: 57898-80-3) might be present as an impurity during the synthesis of Acebutolol that is used in the treatment of hypertension. It is a cardioselective β-adrenoceptor blocking agent with partial agonist and membrane stabilizing properties.
References Rakibe, Uday, et al. “LC and LC–MS/MS Studies for the Identification and Characterization of Degradation Products of Acebutolol.” Journal of Pharmaceutical Analysis, vol. 8, no. 6, Dec. 2018, pp. 357–65, https://doi.org/10.1016/j.jpha.2018.03.001. ‌

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