| Name: | Acebutolol EP Impurity I |
| Catalogue No. | VL4900010 |
| CAS No. | 441019-91-6 |
| Molecular Formula | C17H26N2O4 |
| Molecular Weight | 322.4 |
| Status | Under Development |
| IUPAC Name | N-[3-Acetyl-4-[3-(ethylamino)-2-hydroxypropoxy]phenyl]butanamide |
| Synonyms | Acebutolol USP Related Compound I |
| Description | Acebutolol EP Impurity I (CAS No: 441019-91-6) or Acebutolol USP Related Compound I/rac N-Desisopropyl-N-ethyl is a degradation product of Acebutolol that is a β-adrenolytic drug utilized in the treatment of hypertension, which is the principal risk factor of coronary arterial disease, coronary arterial incidents, chronic renal failure, and hypostatic cardiac insufficiency. |
| References | Ogrodowczyk, Magdalena, et al. “Identification of Radiodegradation Products of Acebutolol and Alprenolol by HPLC/MS/MS.” Journal of AOAC INTERNATIONAL, vol. 98, no. 1, Jan. 2015, pp. 46–50, https://doi.org/10.5740/jaoacint.14-096. |
