
Name: | Adefovir Dipivoxil Impurity 1 |
Catalogue No. | VL5400021 |
CAS No. | 1215101-40-8 |
Molecular Formula | C25H40N5O8P |
Molecular Weight | 569.587561 g/mol |
Status | In-Stock |
IUPAC Name | ((((2-(6-pivalamido-9H-purin-9-yl)ethoxy)methyl)phosphinediyl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate) |
Description | Adefovir Dipivoxil Impurity 1 (CAS No: 1215101-40-8) is a degradation product of Adefovir dipivoxil that is a bis(pivaloyloxymethyl) prodrug of adefovir with chemical stability problems. Adefovir is an antiviral drug used in the treatment of various viral infections. |
References | Gao, Yuan, et al. “Coformer Selection Based on Degradation Pathway of Drugs: A Case Study of Adefovir Dipivoxil–Saccharin and Adefovir Dipivoxil–Nicotinamide Cocrystals.” International Journal of Pharmaceutics, vol. 438, no. 1-2, Nov. 2012, pp. 327–35, https://doi.org/10.1016/j.ijpharm.2012.09.027. Yuan, Lung-Chi. Pharmaceutical Research, vol. 17, no. 9, 2000, pp. 1098–103, https://doi.org/10.1023/a:1026457729708. |