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Adefovir Dipivoxil Impurity 1

Adefovir Dipivoxil Impurity 1

Catalogue No.: VL5400021
CAS No.: 1215101-40-8

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Name: Adefovir Dipivoxil Impurity 1
Catalogue No. VL5400021
CAS No. 1215101-40-8
Molecular Formula C25H40N5O8P
Molecular Weight 569.587561 g/mol
Status In-Stock
IUPAC Name ((((2-(6-pivalamido-9H-purin-9-yl)ethoxy)methyl)phosphinediyl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
Description Adefovir Dipivoxil Impurity 1 (CAS No: 1215101-40-8) is a degradation product of Adefovir dipivoxil that is a bis(pivaloyloxymethyl) prodrug of adefovir with chemical stability problems. Adefovir is an antiviral drug used in the treatment of various viral infections.
References Gao, Yuan, et al. “Coformer Selection Based on Degradation Pathway of Drugs: A Case Study of Adefovir Dipivoxil–Saccharin and Adefovir Dipivoxil–Nicotinamide Cocrystals.” International Journal of Pharmaceutics, vol. 438, no. 1-2, Nov. 2012, pp. 327–35, https://doi.org/10.1016/j.ijpharm.2012.09.027. Yuan, Lung-Chi. Pharmaceutical Research, vol. 17, no. 9, 2000, pp. 1098–103, https://doi.org/10.1023/a:1026457729708.

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