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Afatinib Amino Pyrrolidinone Impurity

Afatinib Amino Pyrrolidinone Impurity

Catalogue No.: VL5510060
CAS No.: N/A

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Name: Afatinib Amino Pyrrolidinone Impurity
Catalogue No. VL5510060
CAS No. N/A
Molecular Formula C22H21ClFN5O3
Molecular Weight 457.89 g/mol
Status In-Stock
IUPAC Name 5-Amino-1-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tetrahydrofuran-3-yloxy)quinazolin-6-yl)pyrrolidin-2-one
Description Afatinib Amino Pyrrolidinone Impurity(CAS No: N/A) or 5-amino-1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)pyrrolidin-2-one, is a second-generation epidermal growth factor receptor-tyrosine kinase inhibitor that is used in the treatment of metastatic non-small cell lung cancer.
References Ricciuti, Biagio, et al. “Afatinib in the First-Line Treatment of Patients with Non-Small Cell Lung Cancer: Clinical Evidence and Experience.” Therapeutic Advances in Respiratory Disease, vol. 12, 25 Oct. 2018, p. 1753466618808659, www.ncbi.nlm.nih.gov/pmc/articles/PMC6204616/, 10.1177/1753466618808659. Accessed 24 Jan. 2022.

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