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Afatinib Dimaleate

Afatinib Dimaleate

Catalogue No.: VL5510061
CAS No.: 850140-73-7

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Name: Afatinib Dimaleate
Catalogue No. VL5510061
CAS No. 850140-73-7
Molecular Formula C₂₄H₂₅ClFN₅O₃ • [C₄H₄O₄]₂
Molecular Weight 718.10 g/mol
Status In-Stock
IUPAC Name (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide (2Z)-2-butenedioate
Description Afatinib dimaleate (CAS No: 850140-73-7) is an anilinoquinazoline derivative that is an irreversible tyrosine kinase receptor inhibitor utilised in the treatment of metastatic non-small cell lung cancer that is the common type of lung cancer.
References Chavan, Balasaheb B., et al. “Isolation and Structural Characterization of Degradation Products of Afatinib Dimaleate by LC-Q-TOF/MS/MS and NMR: Cytotoxicity Evaluation of Afatinib and Isolated Degradation Products.” Journal of Pharmaceutical and Biomedical Analysis, vol. 166, Mar. 2019, pp. 139–46, https://doi.org/10.1016/j.jpba.2019.01.004.

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