| Name: | Afatinib Dimaleate |
| Catalogue No. | VL5510061 |
| CAS No. | 850140-73-7 |
| Molecular Formula | C₂₄H₂₅ClFN₅O₃ • [C₄H₄O₄]₂ |
| Molecular Weight | 718.10 g/mol |
| Status | In-Stock |
| IUPAC Name | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide (2Z)-2-butenedioate |
| Description | Afatinib dimaleate (CAS No: 850140-73-7) is an anilinoquinazoline derivative that is an irreversible tyrosine kinase receptor inhibitor utilised in the treatment of metastatic non-small cell lung cancer that is the common type of lung cancer. |
| References | Chavan, Balasaheb B., et al. “Isolation and Structural Characterization of Degradation Products of Afatinib Dimaleate by LC-Q-TOF/MS/MS and NMR: Cytotoxicity Evaluation of Afatinib and Isolated Degradation Products.” Journal of Pharmaceutical and Biomedical Analysis, vol. 166, Mar. 2019, pp. 139–46, https://doi.org/10.1016/j.jpba.2019.01.004. |
