| Name: | Afatinib Impurity A |
| Catalogue No. | VL5510004 |
| CAS No. | N/A |
| Molecular Formula | C18H14ClFN4O4 |
| Molecular Weight | 404.79 |
| Status | Under Development |
| IUPAC Name | (R)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine |
| Description | Afatinib Impurity A(CAS No: N/A) or (R)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine,Afatinib Impurity A is an impurityoof Afatinib,is a second-generation epidermal growth factor receptor-tyrosine kinase inhibitor that is used in the treatment of metastatic non-small cell lung cancer. |
| References | Wang, Chi, et al. “The Impact of Afatinib on Survival in Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials.” Journal of Cancer, vol. 10, no. 4, 2019, pp. 885–892, 10.7150/jca.27528. |
