
Name: | Afatinib Impurity D |
Catalogue No. | VL5510007 |
CAS No. | N/A |
Molecular Formula | C24H25ClFN5O3 |
Molecular Weight | 485.95 |
Status | In-stock |
IUPAC Name | (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide |
Description | Afatinib Impurity D(CAS No: N/A) or (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide,Afatinib Impurity D is an impurity of Afatinib,it is a 4-anilinoquinazoline tyrosine kinase inhibitor that is used for patients with metastatic non-small cell lung cancer. |
References | Ricciuti, Biagio, et al. “Afatinib in the First-Line Treatment of Patients with Non-Small Cell Lung Cancer: Clinical Evidence and Experience.” Therapeutic Advances in Respiratory Disease, vol. 12, 25 Oct. 2018, p. 1753466618808659, www.ncbi.nlm.nih.gov/pmc/articles/PMC6204616/, 10.1177/1753466618808659. |