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Afatinib Impurity F

Afatinib Impurity F

Catalogue No.: VL5510009
CAS No.: N/A

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Name: Afatinib Impurity F
Catalogue No. VL5510009
Molecular Formula C24H25F2N5O3
Molecular Weight 469.50
Status Under Development
IUPAC Name (S,Z)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Description Afatinib Impurity F(CAS No: N/A) or (S,Z)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide,Afatinib Impurity F is an impurity of Afatinib,it is a 4-anilinoquinazoline tyrosine kinase inhibitor that is used for patients with metastatic non-small cell lung cancer.
References Wang, Chi, et al. “The Impact of Afatinib on Survival in Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials.” Journal of Cancer, vol. 10, no. 4, 2019, pp. 885–892, 10.7150/jca.27528.

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