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Afatinib Impurity I

Afatinib Impurity I

Catalogue No.: VL5510012
CAS No.: N/A

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Name: Afatinib Impurity I
Catalogue No. VL5510012
Molecular Formula C22H19BrClFN4O3
Molecular Weight 521.78
Status Under Development
IUPAC Name (S,Z)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Description Afatinib Impurity I(CAS No: N/A) or (S,Z)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide,Afatinib Impurity I is an impurity of Afatinib, is an antineoplastic agent and 4-anilinoquinazoline tyrosine kinase inhibitor that is used to treat a certain type of lung cancer.
References Wang, Chi, et al. “The Impact of Afatinib on Survival in Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials.” Journal of Cancer, vol. 10, no. 4, 2019, pp. 885–892, 10.7150/jca.27528.

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