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Afatinib N-Oxide Impurity

Afatinib N-Oxide Impurity

Catalogue No.: VL5510023
CAS No.: N/A

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Name: Afatinib N-Oxide Impurity
Catalogue No. VL5510023
CAS No. N/A
Molecular Formula C24H25ClFN5O4
Molecular Weight 501.94
Status Under Development
IUPAC Name (S,Z)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide
Description Afatinib N-Oxide Impurity(CAS No: N/A) or (S,Z)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide, is a potent and selective, irreversible tyrosine kinase inhibitor,
References Ricciuti, Biagio, et al. “Afatinib in the First-Line Treatment of Patients with Non-Small Cell Lung Cancer: Clinical Evidence and Experience.” Therapeutic Advances in Respiratory Disease, vol. 12, 25 Oct. 2018, p. 1753466618808659, www.ncbi.nlm.nih.gov/pmc/articles/PMC6204616/, 10.1177/1753466618808659.

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