| Name: | Agomelatine Desmethyl 3 Hydroxy Impurity |
| Catalogue No. | VL1840010 |
| CAS No. | 166527-00-0 |
| Molecular Formula | C14H15NO3 |
| Molecular Weight | 245.28 |
| Status | Under Development |
| IUPAC Name | N-[2-(3,7-dihydroxy-1-naphthalenyl)ethyl]acetamide |
| Synonyms | 7-Desmethyl-3-hydroxyagomelatine |
| Description | Agomelatine Desmethyl 3 Hydroxy Impurity (CAS No: 166527-00-0) or 7-Desmethyl-3-hydroxyagomelatine is a metabolite of agomelatine that is a napthalenic compound is a specific agonist of MT1 and MT2, and a selective antagonist of 5-HT2c receptors. |
| References | Li, Meizhen, et al. “Development and Validation a LC–MS/MS Method for the Simultaneous Determination of Agomelatine and Its Metabolites, 7-Desmethyl-Agomelatine and 3-Hydroxy-Agomelatine in Human Plasma: Application to a Bioequivalence Study.” Journal of Chromatography B, vol. 1003, Oct. 2015, pp. 60–66, https://doi.org/10.1016/j.jchromb.2015.09.018. |
