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Agomelatine Desmethyl 3 Hydroxy Impurity

Agomelatine Desmethyl 3 Hydroxy Impurity

Catalogue No.: VL1840010
CAS No.: 166527-00-0

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Name: Agomelatine Desmethyl 3 Hydroxy Impurity
Catalogue No. VL1840010
CAS No. 166527-00-0
Molecular Formula C14H15NO3
Molecular Weight 245.28
Status Under Development
IUPAC Name N-[2-(3,7-dihydroxy-1-naphthalenyl)ethyl]acetamide
Synonyms 7-Desmethyl-3-hydroxyagomelatine
Description Agomelatine Desmethyl 3 Hydroxy Impurity (CAS No: 166527-00-0) or 7-Desmethyl-3-hydroxyagomelatine is a metabolite of agomelatine that is a napthalenic compound is a specific agonist of MT1 and MT2, and a selective antagonist of 5-HT2c receptors.
References Li, Meizhen, et al. “Development and Validation a LC–MS/MS Method for the Simultaneous Determination of Agomelatine and Its Metabolites, 7-Desmethyl-Agomelatine and 3-Hydroxy-Agomelatine in Human Plasma: Application to a Bioequivalence Study.” Journal of Chromatography B, vol. 1003, Oct. 2015, pp. 60–66, https://doi.org/10.1016/j.jchromb.2015.09.018.

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