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Agomelatine Diacetyl Impurity

Agomelatine Diacetyl Impurity

Catalogue No.: VL1840003
CAS No.: 1379005-34-1

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Name: Agomelatine Diacetyl Impurity
Catalogue No. VL1840003
CAS No. 1379005-34-1
Molecular Formula C17H19NO3
Molecular Weight 285.35
Status Under Development
IUPAC Name N-acetyl-N-(2-(7-methoxynaphthalen-1-yl)ethyl)acetamide
Description Agomelatine Diacetyl Impurity (CAS No: 1379005-34-1) or N-acetyl-N-(2-(7-methoxynaphthalen-1-yl)ethyl)acetamide is an impurity of Agomelatine that is used as an effective melatonergic antidepressant. It acts by combining its melatonin MT1 and MT2 agonist properties with a serotonin 5-HT2C antagonist effect.
References “Simple and Efficient Process for the Large-Scale Preparation of Agomelatine: An Antidepressant Drug.” Synthetic Communications, 2015, www.tandfonline.com/doi/abs/10.1080/00397911.2015.1050524.

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