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Agomelatine Dimer Urea

Agomelatine Dimer Urea

Catalogue No.: VL1840008
CAS No.: 185421-27-6

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Name: Agomelatine Dimer Urea
Catalogue No. VL1840008
CAS No. 185421-27-6
Molecular Formula C27H28N2O3
Molecular Weight 428.53
Status Under Development
IUPAC Name N,N’-Bis[2-(7-methoxy-1-naphthalenyl)ethyl]urea
Synonyms Agomelatine Impurity 4
Description Agomelatine Dimer Urea (CAS No: 185421-27-6) or Agomelatine Impurity 4 chemically known as N, N’-Bis[2-(7-methoxy-1-naphthalenyl)ethyl]urea is an impurity of Agomelatine that is a melatonin analogue, that represents a new class of antidepressants. It is a potent melatonergic agonist and also has 5-hydrotryptamine 2C antagonist properties.
References Liu, Yaxuan, et al. “Quantification and Structural Elucidation of Potential Impurities in Agomelatine Active Pharmaceutical Ingredient.” Journal of Pharmaceutical and Biomedical Analysis, vol. 81-82, July 2013, pp. 193–201, https://doi.org/10.1016/j.jpba.2013.04.016.

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