Alfacalcidol EP Impurity A

Alfacalcidol EP Impurity A

Catalogue No.: VL5740002
CAS No.: 65445-14-9

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Name: Alfacalcidol EP Impurity A
Catalogue No. VL5740002
CAS No. 65445-14-9
Molecular Formula C27H44O2
Molecular Weight 400.64 g/mol
Status In-Stock
IUPAC Name (5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1a,3ß-diol
Synonyms trans-Alfacalcidol
Description Alfacalcidol EP Impurity A (CAS No: 65445-14-9) or trans-Alfacalcidol is an impurity formed in Alfacalcidol that is a synthetic analog of Calcitiol, which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source.
References Holick, M. F., et al. “1α-Hydroxy Derivative of Vitamin D 3 : A Highly Potent Analog of 1α,25-Dihydroxyvitamin D 3.” Science, vol. 180, no. 4082, Apr. 1973, pp. 190–91, https://doi.org/10.1126/science.180.4082.190. de Nijs, Ron N. J., et al. “Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis.” New England Journal of Medicine, vol. 355, no. 7, Aug. 2006, pp. 675–84, https://doi.org/10.1056/nejmoa053569.

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