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Alfacalcidol EP Impurity C

Alfacalcidol EP Impurity C

Catalogue No.: VL5740004
CAS No.: 82266-85-1

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Name: Alfacalcidol EP Impurity C
Catalogue No. VL5740004
CAS No. 82266-85-1
Molecular Formula C35H49N3O4
Molecular Weight 575.78 g/mol
Status In-Stock
IUPAC Name 6.-[(3S,5R)-3,5-Dihydroxy-2-methylcyclohex-1-en-1-yl]-2-phenyl-2,5,10-triaza-4,19-dinor-9.-cholest-7-ene-1,3-dione
Synonyms pre-Alfacalcidol PTAD Adduct
Description Alfacalcidol EP Impurity C (cas no-82266-85-1); IUPAC Name-[(3S,5R)-3,5-Dihydroxy-2-methylcyclohex-1-en-1-yl]-2-phenyl-2,5,10-triaza-4,19-dinor-9.-cholest-7-ene-1,3-dione. Its an impurity of alfacalcidol, it a used in the treatment of patients with renal failure. It safely and beneficially modifies renal bone diseases in patients. It is given in combination with glucocorticoids for the treatment of rheumatic diseases.
References Hamdy, N. A. T., et al. “Effect of Alfacalcidol on Natural Course of Renal Bone Disease in Mild to Moderate Renal Failure.” BMJ, vol. 310, no. 6976, Feb. 1995, pp. 358–63, https://doi.org/10.1136/bmj.310.6976.358. de Nijs, Ron N. J., et al. “Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis.” New England Journal of Medicine, vol. 355, no. 7, Aug. 2006, pp. 675–84, https://doi.org/10.1056/nejmoa053569.

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