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Aliskiren Carboxylic Acid Impurity

Aliskiren Carboxylic Acid Impurity

Catalogue No.: VL5780008
CAS No.: 173400-13-0

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Name: Aliskiren Carboxylic Acid Impurity
Catalogue No. VL5780008
CAS No. 173400-13-0
Molecular Formula C30H52N2O7
Molecular Weight 552.74 g/mol
Status In-Stock
IUPAC Name 3-[[(2S,4S,5S,7S)-5-Amino-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl] methyl]-8-methyl-2-(1-methylethyl)-1-oxononyl]amino]-2,2-dimethyl-propanoic acid
Description Aliskiren Carboxylic Acid Impurity (CAS No: 173400-13-0) is a metabolite formed during the industrial synthesis of Aliskiren that is applied during the treatment of hypertension and serves by selectively inhibiting renin which is an enzyme effective in the conversion of angiotensinogen to angiotensin-I.
References Kushwah, Bhoopendra Singh, et al. “Characterization of Solution Stress Degradation Products of Aliskiren and Prediction of Their Physicochemical and ADMET Properties.” European Journal of Pharmaceutical Sciences, vol. 121, Aug. 2018, pp. 139–54,https://doi.org/10.1016/j.ejps.2018.05.021.

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