
Name: | Aliskiren Hemifumarate (RRRS isomer) Impurity |
Catalogue No. | VL5780009 |
CAS No. | N/A |
Molecular Formula | C30H53N3O6. 0.5 C4H4O4 |
Molecular Weight | 551.77 0.5 116.07 g/mol |
Status | In-Stock |
IUPAC Name | (2R,4R,5R,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate |
Description | Aliskiren Hemifumarate (RRRS isomer) Impurity (cas no.-) IUPAC Name-(2R,4R,5R,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate.Its an impurity of Aliskiren, Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone or in combination |
References | Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008. |