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Aliskiren Hemifumarate (SSSR isomer) Impurity

Aliskiren Hemifumarate (SSSR isomer) Impurity

Catalogue No.: VL5780010
CAS No.: N/A

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Name: Aliskiren Hemifumarate (SSSR isomer) Impurity
Catalogue No. VL5780010
CAS No. N/A
Molecular Formula C30H53N3O6. 0.5 C4H4O4
Molecular Weight 551.77 0.5 116.07 g/mol
Status In-Stock
IUPAC Name (2S,4S,5S,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate
Description Aliskiren Hemifumarate (SSSR isomer) Impurity (cas no.-) IUPAC Name-(2S,4S,5S,7R)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate.Its an impurity of Aliskiren, Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone or in combination
References Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008.

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