
Name: | Aliskiren O Desmethoxypropyl Impurity |
Catalogue No. | VL5780016 |
CAS No. | 949925-77-3 |
Molecular Formula | C26H45N3O5 |
Molecular Weight | 479.65 g/mol |
Status | In-Stock |
IUPAC Name | (αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ,3-dihydroxy-4-methoxy-α,ζ-bis(1-methylethyl)benzeneoctanamide |
Description | Aliskiren O Desmethoxypropyl Impurity (cas no.-949925-77-3) IUPAC Name-(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate. Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone or in combination with other antihypertensive agents. |
References | Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008. |