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Aliskiren O Desmethoxypropyl Impurity

Aliskiren O Desmethoxypropyl Impurity

Catalogue No.: VL5780016
CAS No.: 949925-77-3

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Name: Aliskiren O Desmethoxypropyl Impurity
Catalogue No. VL5780016
CAS No. 949925-77-3
Molecular Formula C26H45N3O5
Molecular Weight 479.65 g/mol
Status In-Stock
IUPAC Name (αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ,3-dihydroxy-4-methoxy-α,ζ-bis(1-methylethyl)benzeneoctanamide
Description Aliskiren O Desmethoxypropyl Impurity (cas no.-949925-77-3) IUPAC Name-(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate. Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone or in combination with other antihypertensive agents.
References Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008.

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