| Name: | Alvimopan Impurity 14 |
| Catalogue No. | VE007904 |
| CAS No. | 76932-18-8 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Status | In-Stock |
| IUPAC Name | (2-benzylacryloyl)glycine |
| Description | Alvimopan Impurity 14 (CAS No: 76932-18-8) or (2-benzylacryloyl)glycineis an impurity of alvimopan. Molecular formula-C12H13NO3; Molecular weight-219.2, it is an opioid receptor antagonist in development for the management of postoperative ileus.it is used to treatment and recover of gastrointestinal (GI) function in patients undergoing laparotomy for bowel resection or radical hysterectomy. |
| References | Wolff, Bruce G., et al. “Alvimopan, a Novel, Peripherally Acting μ Opioid Antagonist.” Annals of Surgery, vol. 240, no. 4, Oct. 2004, pp. 728–35, https://doi.org/10.1097/01.sla.0000141158.27977.66. Erowele, Goldina Ikezuagu. “Alvimopan (Entereg), a Peripherally Acting Mu-Opioid Receptor Antagonist for Postoperative Ileus.” Pharmacy and Therapeutics, vol. 33, no. 10, Oct. 2008, pp. 574–83, www.ncbi.nlm.nih.gov/pmc/articles/PMC2730789/. |
