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Alvimopan Impurity 14

Alvimopan Impurity 14

Catalogue No.: VE007904
CAS No.: 76932-18-8

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Name: Alvimopan Impurity 14
Catalogue No. VE007904
CAS No. 76932-18-8
Molecular Formula C12H13NO3
Molecular Weight 219.24 g/mol
Status In-Stock
IUPAC Name (2-benzylacryloyl)glycine
Description Alvimopan Impurity 14 (CAS No: 76932-18-8) or (2-benzylacryloyl)glycineis an impurity of alvimopan. Molecular formula-C12H13NO3; Molecular weight-219.2, it is an opioid receptor antagonist in development for the management of postoperative ileus.it is used to treatment and recover of gastrointestinal (GI) function in patients undergoing laparotomy for bowel resection or radical hysterectomy.
References Wolff, Bruce G., et al. “Alvimopan, a Novel, Peripherally Acting μ Opioid Antagonist.” Annals of Surgery, vol. 240, no. 4, Oct. 2004, pp. 728–35, https://doi.org/10.1097/01.sla.0000141158.27977.66. Erowele, Goldina Ikezuagu. “Alvimopan (Entereg), a Peripherally Acting Mu-Opioid Receptor Antagonist for Postoperative Ileus.” Pharmacy and Therapeutics, vol. 33, no. 10, Oct. 2008, pp. 574–83, www.ncbi.nlm.nih.gov/pmc/articles/PMC2730789/.

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