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Alvimopan Impurity 27

Alvimopan Impurity 27

Catalogue No.: VE007914
CAS No.: 119193-19-0

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Name: Alvimopan Impurity 27
Catalogue No. VE007914
CAS No. 119193-19-0
Molecular Formula C13H19NO
Molecular Weight 205.3 g/mol
Status In-Stock
IUPAC Name 3-((3R,4R)-3,4-dimethylpiperidin-4-yl)phenol
Synonyms [(3R,4R)-3,4-Dimethylpiperidin-4-yl]phenol
Description Alvimopan Impurity 27 (CAS No: 119193-19-0) or [(3R,4R)-3,4-Dimethylpiperidin-4-yl]phenol is formed by degradation of alvimopan that acts peripherally by antagonist mu-opioid receptor (PAM-OR) and is utilised in the treatment of postoperative ileus.
References Baira, Shandilya Mahamuni, et al. “Identification and Structural Characterization of Hydrolytic Degradation Products of Alvimopan by LC/QTOF/MS/MS and NMR Studies.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 399–409,https://doi.org/10.1016/j.jpba.2018.12.035.

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