| Name: | Alvimopan Impurity 6 |
| Catalogue No. | VL5980005 |
| CAS No. | 1420776-96-0 |
| Molecular Formula | C24H29NO3 . HCl |
| Molecular Weight | 379.50 36.46 g/mol |
| Status | In-Stock |
| IUPAC Name | (E)-methyl 2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-phenylacrylate hydrochloride |
| Description | Alvimopan Impurity 6 (CAS No: 1420776-96-0) is an impurity observed in Alvimopan that is an opioid drug that acts peripherally by antagonist mu-opioid receptor (PAM-OR) and is utilised in the treatment of postoperative ileus. It is also used in the treatment of post-operative ileus and chronic idiopathic constipation. |
| References | Ramalinga Reddy, Beeravalli, et al. “Synthesis and Characterization of All Possible Diastereoisomers of Alvimopan.” Oriental Journal of Chemistry, vol. 34, no. 2, Apr. 2018, pp. 963–72,https://doi.org/10.13005/ojc/340246.Baira, Shandilya Mahamuni, et al. “Identification and Structural Characterization of Hydrolytic Degradation Products of Alvimopan by LC/QTOF/MS/MS and NMR Studies.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 399–409,https://doi.org/10.1016/j.jpba |
