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Ambrisentan 4-Hydroxymethyl Analog

Ambrisentan 4-Hydroxymethyl Analog

Catalogue No.: VL6020013
CAS No.: 1106685-66-8

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Name: Ambrisentan 4-Hydroxymethyl Analog
Catalogue No. VL6020013
CAS No. 1106685-66-8
Molecular Formula C22H22N2O5
Molecular Weight 394.42 g/mol
Status In-Stock
IUPAC Name (S)-4-Hydroxymethyl Ambrisentan ; (+)-(2S)-2-[(6-Methyl-4-hydroxymethyl-pyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid
Description Ambrisentan 4 Hydroxymethyl Analog (CAS No: 1106685-66-8) or (S)-4-Hydroxymethyl Ambrisentan is a major metabolite of Ambrisentan that is a highly selective antagonist of the endothelin-1 type A receptor and is indicated for the treatment of pulmonary arterial hypertension.
References Frampton, James E. “Ambrisentan.” American Journal Cardiovascular Drugs, vol. 11, no. 4, Aug. 2011, pp. 215–26,https://doi.org/10.2165/11207340-000000000-00000.

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