
Name: | Ambrisentan 4-Hydroxymethyl Analog |
Catalogue No. | VL6020013 |
CAS No. | 1106685-66-8 |
Molecular Formula | C22H22N2O5 |
Molecular Weight | 394.42 g/mol |
Status | In-Stock |
IUPAC Name | (S)-4-Hydroxymethyl Ambrisentan ; (+)-(2S)-2-[(6-Methyl-4-hydroxymethyl-pyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid |
Description | Ambrisentan 4 Hydroxymethyl Analog (CAS No: 1106685-66-8) or (S)-4-Hydroxymethyl Ambrisentan is a major metabolite of Ambrisentan that is a highly selective antagonist of the endothelin-1 type A receptor and is indicated for the treatment of pulmonary arterial hypertension. |
References | Frampton, James E. “Ambrisentan.” American Journal Cardiovascular Drugs, vol. 11, no. 4, Aug. 2011, pp. 215–26,https://doi.org/10.2165/11207340-000000000-00000. |