Ambrisentan Ethyl Ester

Ambrisentan Ethyl Ester

Catalogue No.: VL6020017
CAS No.: 1349854-31-4

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Name: Ambrisentan Ethyl Ester
Catalogue No. VL6020017
CAS No. 1349854-31-4
Molecular Formula C24H26N2O4
Molecular Weight 406.47 g/mol
Status In-Stock
IUPAC Name ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate
Description Ambrisentan Ethyl Ester (CAS No: 1349854-31-4) or ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate is a derivative of Ambrisentan that is used in the therapy of pulmonary arterial hypertension (PAH) that acts by blocking the effects of a substance called endothelin.
References Feng, Wei-Dong, et al. “Isolation, Identification, Characterization, Synthesis and Quality Control Strategy of New Process-Related Impurities in Ambrisentan.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 325–37,https://doi.org/10.1016/j.jpba.2018.12.008.Pasquini, Benedetta, et al. “Combined Approach Using Capillary Electrophoresis, NMR and Molecular Modeling for Ambrisentan Related Substances Analysis: Investigation of Intermolecular Affinities, Complexation and Se

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