| Name: | Ambrisentan Hydroxy Acid Impurity |
| Catalogue No. | VE007958 |
| CAS No. | 178306-49-5 |
| Molecular Formula | C16H16O4 |
| Molecular Weight | 272.3 g/mol |
| Status | In-Stock |
| IUPAC Name | (R)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid |
| Description | Ambrisentan Hydroxy Acid Impurity (CAS No: 178306-49-5) or (R)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid is an impurity present in the ambrisentan that acts by blocking the effects of a substance called endothelin that is generated by the body in increased amounts in patients with pulmonary arterial hypertension |
| References | Feng, Wei-Dong, et al. “Isolation, Identification, Characterization, Synthesis and Quality Control Strategy of New Process-Related Impurities in Ambrisentan.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 325–37,https://doi.org/10.1016/j.jpba.2018.12.008. |
