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Ambrisentan Impurity E

Ambrisentan Impurity E

Catalogue No.: VL6020015
CAS No.: 1312092-82-2

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Name: Ambrisentan Impurity E
Catalogue No. VL6020015
CAS No. 1312092-82-2
Molecular Formula C21H18N2O3
Molecular Weight 346.39 g/mol
Status In-Stock
IUPAC Name 2-((4,6-dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid
Description Ambrisentan Impurity E (CAS No: 1312092-82-2) or 2-((4,6-dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid is an impurity in the synthesis of Ambrisentan that is an endothelin receptor antagonist designated for the treatment of pulmonary arterial hypertension.
References Feng, Wei-Dong, et al. “Isolation, Identification, Characterization, Synthesis and Quality Control Strategy of New Process-Related Impurities in Ambrisentan.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 325–37,https://doi.org/10.1016/j.jpba.2018.12.008.

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