
Name: | Ambrisentan Methyl Ester Racemate |
Catalogue No. | VL6020019 |
CAS No. | 1240470-84-1 |
Molecular Formula | C23H24N2O4 |
Molecular Weight | 392.45 g/mol |
Status | In-Stock |
IUPAC Name | 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid methyl ester |
Description | Ambrisentan Methyl Ester Racemate (CAS No: 1240470-84-1) or 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid methyl ester is an intermediate of Ambrisentan that is utilized in the treatment of pulmonary arterial hypertension |
References | Feng, Wei-Dong, et al. “Isolation, Identification, Characterization, Synthesis and Quality Control Strategy of New Process-Related Impurities in Ambrisentan.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 325–37,https://doi.org/10.1016/j.jpba.2018.12.008.Pasquini, Benedetta, et al. “Combined Approach Using Capillary Electrophoresis, NMR and Molecular Modeling for Ambrisentan Related Substances Analysis: Investigation of Intermolecular Affinities, Complexation and Se |