|Molecular Weight||378.42 g/mol|
|IUPAC Name||(-)-(2R)-2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ; (R)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic Acid|
|Description||Ambrisentan (R)-Isomer (CAS No: 1007358-76-0) chemically known as (-)-(2R)-2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid is an enantiomer of S-ambrisentan that is a chiral drug used for the treatment of pulmonary arterial hypertension and in the therapy of migraine and cluster headaches.|
|References||Pasquini, Benedetta, et al. “Combined Approach Using Capillary Electrophoresis, NMR and Molecular Modeling for Ambrisentan Related Substances Analysis: Investigation of Intermolecular Affinities, Complexation and Separation Mechanism.” Journal of Pharmaceutical and Biomedical Analysis, vol. 144, Sept. 2017, pp. 220–29,https://doi.org/10.1016/j.jpba.2017.01.038.|
Ambrisentan Acyl Glucuronide (Mixture of Diastereomers)
Catalogue No. VL6020010
CAS No. 1106685-82-8
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