
Name: | Ambrisentan Vinyloxy Impurity |
Catalogue No. | VL6020011 |
CAS No. | 1639429-81-4 |
Molecular Formula | C20H18N2O |
Molecular Weight | 302.38 g/mol |
Status | In-Stock |
IUPAC Name | 2-((2,2-diphenylvinyl)oxy)-4,6-dimethylpyrimidine |
Description | Ambrisentan Vinyloxy Impurity (CAS No: 1639429-81-4) or 2-((2,2-diphenylvinyl)oxy)-4,6-dimethylpyrimidine is an impurity formed during the synthesis of Ambrisentan that is used in the treatment of pulmonary arterial hypertension (PAH) that acts by blocking the effects of a substance called endothelin, which is generated by the body in increased amounts in patients with PAH |
References | Narayana, M. B. V., et al. “A Validated Specific Stability-Indicating RP-HPLC Assay Method for Ambrisentan and Its Related Substances.” Journal of Chromatographic Science, vol. 52, no. 8, Aug. 2013, pp. 818–25,https://doi.org/10.1093/chromsci/bmt121. |