| Name: | Ambrisentan Vinyloxy Impurity |
| Catalogue No. | VL6020011 |
| CAS No. | 1639429-81-4 |
| Molecular Formula | C20H18N2O |
| Molecular Weight | 302.38 g/mol |
| Status | In-Stock |
| IUPAC Name | 2-((2,2-diphenylvinyl)oxy)-4,6-dimethylpyrimidine |
| Description | Ambrisentan Vinyloxy Impurity (CAS No: 1639429-81-4) or 2-((2,2-diphenylvinyl)oxy)-4,6-dimethylpyrimidine is an impurity formed during the synthesis of Ambrisentan that is used in the treatment of pulmonary arterial hypertension (PAH) that acts by blocking the effects of a substance called endothelin, which is generated by the body in increased amounts in patients with PAH |
| References | Narayana, M. B. V., et al. “A Validated Specific Stability-Indicating RP-HPLC Assay Method for Ambrisentan and Its Related Substances.” Journal of Chromatographic Science, vol. 52, no. 8, Aug. 2013, pp. 818–25,https://doi.org/10.1093/chromsci/bmt121. |
